2019-20 / JULY 1 (CONTRIBUTOR: JOHN CHEVILLE)
35-year-old female presents with hematuria. She has a history of hypertension. Cystoscopy revealed a 3 cm bladder mass and transurethral resection was performed. The tumor is positive for GATA3 and synaptophysin.
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1. What ancillary testing should be done?
a. Immunostain for fumarate hydratase
b. Immunostains for DNA repair enzymes
c. Immunostain for SDH B
d. Immunostain for carbonic anhydrase
2. What feature is most predictive of malignancy?
a. The presence or development of metastases
b. Extension into muscularis propria
c. Clinical symptoms
d. Patient age