Login

Log in



Case of the Week


2019-40 / NOVEMBER 25 (CONTRIBUTOR: LEVENTE KUTHI)


10-year-old girl with 15 cm renal mass and multiple pulmonary metastases. She received neoadjuvant chemotherapy according to the SIOP Umbrella Protocol followed by radical nephrectomy. The immunophenotype was as follows: diffusely positive for vimentin, INI1, CD99, focally positive for cyclin D1, PAX2, S100, and negative for EMA, WT1, AE1/AE3, TLE1, ERG, FLI1, CD56, BCL2, PAX8, desmin. FISH analysis was carried out using EWSR1/FLI1 TriCheck Probe, which identified an EWSR1 rearrangement, but the FLI1 was intact.   







Click on the below thumbnails to enlarge photos.

4 photo(s) Updated on: October 23, 2019


Quiz

1. What is the correct diagnosis?

     a. Clear cell sarcoma of the kidney

     b.  Wilms’ tumor

     c.  Ewing sarcoma

     d.  Desmoplastic small round cell tumor

     e.  Synovial sarcoma

012
345
3167 
3!%
3+5
012
345
3167 
3!%
3+5


    







About GUPS

The Genitourinary Pathology Society (GUPS) was formed with the vision of advancing the care of patients with urologic diseases through enhancements of best practices, research, and education in the subspecialty of Urological Pathology.

GUPS is an official Companion Society of the United States and Canadian Academy of Pathology (USCAP).

Contact

gupathologysociety@gmail.com


Copyright © 2019 Genitourinary Pathology Society
Powered by Wild Apricot Membership Software