2019-11 / APRIL 29 (CONTRIBUTOR: HUIHUI YE)
A 57 year-old male underwent radical prostatectomy for Grade group 2 prostatic adenocarcinoma diagnosed on biopsy. Upon microscopic examination, a glandular lesion was identified in the left anterior prostate, in addition to a large tumor nodule of Grade group 2 cancer in the right posterior. The following images are representative of the left anterior lesion which showed strong and diffuse staining with PAX2 (shown) and racemase, and negativity for PSA and WT-1.
Click on the below thumbnails to enlarge photos.
What is the most likely diagnosis?
a. Prostatic adenocarcinoma with atrophic features
b. Nephrogenic adenoma/metaplasia
c. Mesonephric remnant hyperplasia
d. Simple atrophy of the prostate