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2019-21 / JULY 8 (CONTRIBUTOR: JOHN CHEVILLE)CASE HISTORY |
25-year-old white male presents with large renal mass with pulmonary metastases. A nephrectomy was performed. SDH B immunostain is shown. |
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Quiz |
1. What testing is appropriate for this patient? a. Germline testing for SDH B mutation b. Germline testing for fumarate hydratase mutation c. Mismatch repair enzyme immunohistochemical stains on tumor tissue d. PD-L1 immunohistochemical stain on tumor tissue 2. What other tumors might this patient have? a. Colonic adenocarcinoma b. Extra-adrenal paraganglioma c. Pancreatic islet cell tumor d. B cell lymphoma 3. What of the following features is not a prognostic features in this tumor? a. WHO/ISUP grade b. Sarcomatoid features c. Coagulative tumor necrosis d. Presence of a synchronous paraganglioma |