2019-30 / SEPTEMBER 9 (CONTRIBUTOR: SOUNAK GUPTA)
A 78-year-old male underwent a transurethral resection of the prostate and representative images are shown.
The immunophenotype is as follows:
Positive: CK7 & focal, patchy expression of CK20, CKAE1/3 and CK-HMW
Negative: NKX3.1, PSA, PSAP, P40, GATA3, synaptophysin and chromogranin
Click on the below thumbnails to enlarge photos.
1. What is the correct diagnosis?
a. Poorly differentiated prostatic adenocarcinoma (Gleason grade 5)
b. Adenoid cystic carcinoma
c. Prostatic basal cell carcinoma
d. Poorly differentiated urothelial carcinoma