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Case of the Week

2020-43 / October 26  

Contributor: Daniel Athanazio

A man in his early 50s underwent radical orchiectomy due to a 5.5 cm solid mass in the left testis and a partial orchiectomy for a 1.2 cm solid mass in the right testis. The left testicular mass is shown in figures 1 (gross), 2, 3 and 5. Figure 4 shows the tumor in the right testis, and its transition from a solid mass to areas of intratubular growth (which were absent in the larger mass).

Click on the below thumbnails to enlarge photos.

5 photo(s) Updated on: October 22, 2020
  • Left panel A: c-kit/CD117


1. What is the correct diagnosis?

a) Seminoma with atypia (formerly anaplastic seminoma)  

b) Spermatocytic tumor, anaplastic variant 

c) Anaplastic B-cell lymphoma

d) Epithelioid trophoblastic tumor

e) Embryonal carcinoma

About GUPS

The Genitourinary Pathology Society (GUPS) was formed with the vision of advancing the care of patients with urologic diseases through enhancements of best practices, research, and education in the subspecialty of Urological Pathology.

GUPS is an official Companion Society of the United States and Canadian Academy of Pathology (USCAP).



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