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Case of the Week


2020-5 / FEBRUARY 3 (CONTRIBUTOR: CONSTANTINA PETRAKI)


80 y/o male with hematuria and a bladder tumor. NKX3.1 and prostein immunostains are shown. Otherwise the tumor is positive for AR, PSMA and PSAP and is negative for  GATA3, UroplakinII, CKHMW, p63, CK5/6.









Click on the below thumbnails to enlarge photos.

5 photo(s) Updated on: December 13, 2019


Quiz

1. What is the correct diagnosis?

     a.  Giant cell urothelial carcinoma

     b.  Poorly differentiated urothelial carcinoma with osteoclast-like giant cells

     c.  Pleomorphic giant cell variant of prostatic adenocarcinoma

     d.  Sarcomatoid urothelial carcinoma.

     e.  Urothelial carcinoma with trophoblastic differentiation


    







About GUPS

The Genitourinary Pathology Society (GUPS) was formed with the vision of advancing the care of patients with urologic diseases through enhancements of best practices, research, and education in the subspecialty of Urological Pathology.

GUPS is an official Companion Society of the United States and Canadian Academy of Pathology (USCAP).

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