2021-06 / February 08
Contributors: Aditi Dewan, Sambit K. Mohanty
A man in his mid-60s presented with lower abdominal pain and hematuria. Cystoscopy revealed ulceration of the entire urinary bladder mucosa along with a thickened bladder wall. A transurethral resection of the bladder tumor was performed and submitted for histopathological examination.
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1. What is the correct diagnosis?
d. Signet ring cell carcinoma
e. Plasmacytoid urothelial carcinoma
2. Mutations in which gene are most commonly encountered in the above entity?