2021-12/ March 22
Contributor: Stephanie Conrad, Ming Zhou
A woman in her late 50s with hypertension had an
incidentally discovered 1.7 cm right renal mass. She underwent a right partial
nephrectomy. Presented are the histological findings.
Click on the below thumbnails to enlarge photos.
1. What is the correct diagnosis?
c) Renal cell carcinoma with sarcomatous differentiation
d) Gastrointestinal stromal tumor (GIST)
e) Solitary fibrous tumor
2. Which of the following immunohistochemical assays, when positive expression is present, supports the diagnosis?
d) PAX 8
3. What histological feature supports the diagnosis?
a) Vascular proliferation
b) Rare mitoses
c) Sclerotic background
d) Dysmorphic blood vessels
e) Spindle cell predominance