Log in

Case of the Week

2021-21/ May 24

Contributors:  Max Kong

Male patient in his 80s with prostate biopsy, PSA 0.9 ng/ml. Transurethral resection of the prostate was performed twice in the last two years due to benign prostatic hypertrophy with urinary obstruction.

Click on the below thumbnails to enlarge photos.

8 photo(s) Updated on: May 22, 2021
<< First  < Prev   1   2   Next >  Last >> 
  • HE; 40X
  • HE; 40X
  • HE; 100X
  • HE; 200X
  • PIN4 cocktail (CK5/6, p63, racemase)
<< First  < Prev   1   2   Next >  Last >> 


1.  What is the correct diagnosis?

a) Prostatic adenocarcinoma with mucinous features, Gleason score 4+3=7 (grade group 3)

        b) Prostatic adenocarcinoma with mucinous features and loss of NKX3.1 expression, Gleason score 4+3=7 (grade group 3)

c) Enteric-type/mucinous adenocarcinoma of prostatic urethra, moderately differentiated, involving prostatic tissue

d) Enteric-type/mucinous adenocarcinoma, moderately differentiated, direct invasion or metastatic to prostate from urinary bladder and/or GI tract     

About GUPS

The Genitourinary Pathology Society (GUPS) was formed with the vision of advancing the care of patients with urologic diseases through enhancements of best practices, research, and education in the subspecialty of Urological Pathology.

GUPS is an official Companion Society of the United States and Canadian Academy of Pathology (USCAP).



Copyright © 2019 Genitourinary Pathology Society
Powered by Wild Apricot Membership Software