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Case of the Week

2021-31/ August 2

Contributors:  Dimitris Goutas, Andreas C. Lazaris

A 60-year-old man experiencing voiding difficulties due to prostate gland enlargement, unresponsive to medical treatment, underwent a transurethral resection of the prostate to alleviate his symptoms. Endoscopic evaluation of the prostatic urethra was unremarkable. The patient had no known history of carcinoma.

Click on the below thumbnails to enlarge photos.

5 photo(s) Updated on: August 02, 2021


1.  What is the correct diagnosis?

a. High grade prostate adenocarcinoma

b. Urothelial carcinoma, probably of urinary bladder origin, invading prostatic stroma with large nested pattern

c. Primary invasive urothelial carcinoma of the prostate

d. Intraepithelial extension of urothelial carcinoma to periurethral prostatic ducts and acini

About GUPS

The Genitourinary Pathology Society (GUPS) was formed with the vision of advancing the care of patients with urologic diseases through enhancements of best practices, research, and education in the subspecialty of Urological Pathology.

GUPS is an official Companion Society of the United States and Canadian Academy of Pathology (USCAP).



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