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Case of the Week

2021-37/ September 13

Contributors:  Lagnajita Datta, Sounak Gupta

A female patient in her 50s presented with a 3.9 cm renal mass and underwent partial nephrectomy. On gross examination, a well circumscribed un-encapsulated solid mass with a tan brown cut surface is noted. 

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6 photo(s) Updated on: September 12, 2021
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1.  What is the correct diagnosis?

a.     Oncocytoma

b.     Eosinophilic variant of chromophobe renal cell carcinoma

c.      Eosinophilic vacuolated tumor/ High grade oncocytic tumor (EVT/HOT)

d.     Eosinophilic solid cystic renal cell carcinoma (ESC-RCC)

2.     What is the usual immunoprofile of this tumor?

a.     CD117+/CK7-/CK20-/Cathepsin K+

b.     CD117+/CK7+/CK20-/ Cathepsin K-

c.      CD117-/CK7+/CK20-/ Cathepsin K-

d.     CD117-/CK7-/CK20+/ Cathepsin K-

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The Genitourinary Pathology Society (GUPS) was formed with the vision of advancing the care of patients with urologic diseases through enhancements of best practices, research, and education in the subspecialty of Urological Pathology.

GUPS is an official Companion Society of the United States and Canadian Academy of Pathology (USCAP).



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