2021-37/ September 13
Contributors: Lagnajita Datta, Sounak Gupta
A female patient in her 50s presented with a 3.9 cm renal mass and underwent partial nephrectomy. On gross examination, a well circumscribed un-encapsulated solid mass with a tan brown cut surface is noted.
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1. What is the correct diagnosis?
b. Eosinophilic variant of chromophobe renal cell carcinoma
c. Eosinophilic vacuolated tumor/ High grade oncocytic tumor (EVT/HOT)
d. Eosinophilic solid cystic renal cell carcinoma (ESC-RCC)
2. What is the usual immunoprofile of this tumor?
a. CD117+/CK7-/CK20-/Cathepsin K+
b. CD117+/CK7+/CK20-/ Cathepsin K-
c. CD117-/CK7+/CK20-/ Cathepsin K-
d. CD117-/CK7-/CK20+/ Cathepsin K-