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Case of the Week

2021-38/ September 20

Contributors:  Michelle S. Hirsch, Mark Carter


A woman in her early 30s presented with pelvic pain, and a 2.0 cm kidney mass was incidentally found.


Click on the below thumbnails to enlarge photos.

4 photo(s) Updated on: September 19, 2021
  • Fumarate Hydratase (FH)
  • 2SC


Quiz

1.  What is the correct diagnosis?

a. Oncocytoma

b. Succinate-dehyrogenase deficient RCC

c. Fumarate hydratase-deficient RCC

d. Eosinophilic, solid and cystic RCC

e. Chromophobe RCC


2.    Is there an associated gene mutation with this tumor?

a. No, no specific gene mutation

b. Yes, succinate dehydrogenase (SDH)

c. Yes, fumarate hydratase (FH)

d. Yes, tuberous sclerosis complex (TSC)

e. Yes, p53


3.  What is the correct follow-up for this patient?

a. None, it is a benign tumor

b. Genetic evaluation

c. Routine imaging, including the contralateral kidney

d. Evaluation of parents/siblings/children

e.  Answer choices b - d



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The Genitourinary Pathology Society (GUPS) was formed with the vision of advancing the care of patients with urologic diseases through enhancements of best practices, research, and education in the subspecialty of Urological Pathology.

GUPS is an official Companion Society of the United States and Canadian Academy of Pathology (USCAP).

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