2019-7 / APRIL 1 (CONTRIBUTORS: YUAN GAO, KIRIL TRPKOV)
40-year-old female with a 4.5 cm solid and cystic renal mass. Images are from the radical nephrectomy specimen.
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1. What is the diagnosis?
b. Chromophobe renal cell carcinoma
c. Eosinophilic solid and cystic renal cell carcinoma
d. Epithelioid angiomyolipoma
e. Clear cell renal cell carcinoma, eosinophilic variant
2. What immunohistochemistry is most helpful in resolving your differential diagnosis?
c. PAX 8
d. CD 117
e. Carbonic Anhydrase IX
3. What is the typical gross/macroscopic finding of the above tumor?
a. Non-encapsulated but circumscribed, with a central scar
b. Encapsulated with area of necrosis
c. Solid with macro and micro cysts
d. Golden yellow, infiltrative with area of necrosis
e. Multiple small nodules